| dc.contributor.author | Aydın, Elif Burcu | |
| dc.contributor.author | Sezginturk, Mustafa Kemal | |
| dc.date.accessioned | 2022-08-11T12:31:24Z | |
| dc.date.available | 2022-08-11T12:31:24Z | |
| dc.date.issued | 2021 | en_US |
| dc.identifier.citation | Aydın, E. B., & Sezgintürk, M. K. (2021). Fabrication of Electrochemical Immunosensor for Detection of Interleukin 8 Biomarker via Layer‐by‐layer Self‐assembly Process on Cost‐effective Fluorine Tin Oxide Electrode. Electroanalysis, 33(6), 1596–1605. https://doi.org/10.1002/elan.202060603
| en_US |
| dc.identifier.issn | 1040-0397 / 1521-4109 | |
| dc.identifier.uri | https://doi.org/10.1002/elan.202060603 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12428/3668 | |
| dc.description.abstract | A highly sensitive impedimetric immunosensor for the determination of interleukin 8 (IL 8) cancer biomarker was fabricated via simple fabrication process. A silane agent with isocyanate groups, 3-(triethoxysilyl)propyl isocyanate (IPTES), were utilized for binding of IL 8 antigen specific antibodies and self-assembled on the fluorine tin oxide (FTO) substrate with a standard silanization chemistry. Under optimum experimental conditions, the designed immunosensor had a wide linear detection range of 0.02-4 pg/mL, a low limit of detection of 11.9 fg/mL and a high sensitivity of 4.42 k omega pg(-1) mL cm(-2). The designed biosensor displayed high reproducibility and repeatability, good selectivity against interference biomarkers. | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | Wiley | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Electrochemical Analysis | en_US |
| dc.subject | Chemicals and Materials | en_US |
| dc.subject | Real Sample Analysis | en_US |
| dc.subject | Chemical Characterization | en_US |
| dc.subject | Interleukin | en_US |
| dc.subject | Fluorine tin oxide3 | en_US |
| dc.subject | (triethoxysilyl)Propyl Isocyanate | en_US |
| dc.subject | Disposable Electrode | en_US |
| dc.title | Fabricationof ElectrochemicalImmunosensorforDetectionof Interleukin8 Biomarkervia Layer-by-layerSelf-assemblyProcesson Cost-effectiveFluorineTin OxideElectrode | en_US |
| dc.type | article | en_US |
| dc.authorid | 0000-0003-3042-1087 | en_US |
| dc.relation.ispartof | Electroanalysis | en_US |
| dc.department | Fakülteler, Mühendislik Fakültesi, Biyomühendislik Bölümü | en_US |
| dc.identifier.volume | 33 | en_US |
| dc.identifier.issue | 6 | en_US |
| dc.identifier.startpage | 1596 | en_US |
| dc.identifier.endpage | 1605 | en_US |
| dc.institutionauthor | Sezginturk, Mustafa Kemal | |
| dc.identifier.doi | 10.1002/elan.202060603 | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.authorwosid | AAY-1439-2021 | en_US |
| dc.authorscopusid | 6506764918 | en_US |
| dc.identifier.wosquality | Q3 | en_US |
| dc.identifier.wos | WOS:000631854300001 | en_US |
| dc.identifier.scopus | 2-s2.0-85102957235 | en_US |
