Biyomühendislik Bölümü Koleksiyonu
Güncel Gönderiler
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Development and characterization of skin substitutes from electrospun polycaprolactone/silk fibroin
(SAGE Publications Ltd, 2024)Tissue-engineered skin substitutes have great potential to treat chronic wounds and high-degree burns. Existing solutions, such as Integra Dermal Template, are extensively used for skin defects. However, these templates ... -
Organic-inorganic biohybrid films from wool-keratin/jellyfish-collagen/silica/boron via sol-gel reactions for soft tissue engineering applications
(IOP Publishing, 2024)Therapeutic angiogenesis is pivotal in creating effective tissue-engineered constructs that deliver nutrients and oxygen to surrounding cells. Hence, biomaterials that promote angiogenesis can enhance the efficacy of various ... -
Phosphazene-based nanostructures modified with gold nanoparticles as drug and gene carrier materials with antibacterial and antifungal properties
(Taylor and Francis Ltd., 2024)In this study, monodisperse spherical particles were synthesized by using hexachlorocyclotriphosphazene (HCCP) and 1-(2-Aminoethyl) piperazine (AEP) by the polycondensation reaction. Then, the surfaces of the synthesized ... -
Ultrasensitive detection of NSE employing a novel electrochemical immunosensor based on a conjugated copolymer
(Royal Society of Chemistry, 2024)In the current study a simple and highly specific label-free impedimetric neuron specific enolase (NSE) immunosensor based on a copolymer matrix-coated disposable electrode was designed and tested. The copolymer matrix was ... -
Synthesis and characterization of poly(Maltodextrin) microgel from maltodextrin as drug delivery system
(Elsevier B.V., 2024)Microgels of maltodextrin (MDex) as poly(maltodextrin) (p(MDex)) were prepared by reverse-micelle crosslinking technique at various crosslinking ratios, 25, 50, and 100% based on the repeating unit of MDex using divinylsulfone ... -
Cell Staining Microgels Derived from a Natural Phenolic Dye: Hematoxylin Has Intriguing Biomedical Potential
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Hematoxylin (HT) as a natural phenolic dye compound is generally used together with eosin (E) dye as H&E in the histological staining of tissues. Here, we report for the first time the polymeric particle preparation from ... -
An innovative method for the detection of alpha synuclein, a potential biomarker of Parkinson's disease: quartz tuning fork-based mass sensitive immunosensor design
(Royal Society of Chemistry, 2024)An innovative biosensing fabrication strategy has been demonstrated for the first time using a quartz tuning fork (QTF) to develop a practical immunosensor for sensitive, selective and practical analysis of alpha synuclein ... -
A new immunosensing platform based on conjugated Poly(ThidEp-co-EDOT) copolymer for resistin detection, a new obesity biomarker
(Springer, 2024)The design of a novel electrochemical impedimetric biosensor for label-free analysis of resistin, a biomarker for obesity, is reported. For the fabrication of the immunosensor, a novel approach composed of electrochemical ... -
A Practical Approach for the Detection of Protein Tau with a Portable Potentiostat
(John Wiley and Sons Inc, 2023)Along with many factors, the change in protein tau isoforms, which has an obvious role in the function of microtubules, is an important biomarker of Alzheimer's disease. The aim of this study is to determine the protein ... -
Phosphazene-based nanostructures modified with gold nanoparticles as drug and gene carrier materials with antibacterial and antifungal properties
(Taylor and Francis Ltd., 2023)In this study, monodisperse spherical particles were synthesized by using hexachlorocyclotriphosphazene (HCCP) and 1-(2-Aminoethyl) piperazine (AEP) by the polycondensation reaction. Then, the surfaces of the synthesized ... -
Development of plant-based biopolymer coatings for 3D cell culture: boron-silica-enriched quince seed mucilage nanocomposites
(Royal Society of Chemistry, 2023)Spheroid formation with spontaneous aggregation has captured interest in most cell culture studies due to its easy set-up and more reliable results. However, the economic and technical costs of the advanced systems and ... -
A Review on Phyto-Therapeutic Approaches in Alzheimer's Disease
(MDPI, 2023)Neurodegenerative diseases occur due to progressive and sometimes irreversible loss of function and death of nerve cells. A great deal of effort is being made to understand the pathogenesis of neurodegenerative diseases. ... -
Physically Crosslinked Chondroitin Sulfate (CS)-Metal Ion (M: Fe(III), Gd(III), Zn(II), and Cu(II)) Particles for Versatile Applications and Their Biosafety
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Chondroitin sulfate (CS), a well-known glycosaminoglycan, was physically crosslinked with Fe(III), Gd(III), Zn(II), and Cu(II) ions to obtain CS-Fe(III), CS-Gd(III), CS-Zn(II), and CS-Cu(II) polymeric particles for ... -
Poly(Glycerol) Microparticles as Drug Delivery Vehicle for Biomedical Use
(MDPI, 2023)Glycerol (Gly) is a well-known, FDA-approved molecule posing three hydroxyl groups. Since Gly is biocompatible, here, it was aimed to prepare poly(Glycerol) (p(Gly)) particles directly for the first time for the delivery ... -
Synthesis of p(HEMA-co-AETAC) nanocomposite hydrogel with vinyl-function montmorillonite nanoparticles and effective removal of methyl orange from aqueous solution
(Taylor and Francis Ltd., 2023)It has become crucial to develop new adsorbents to remove toxic dye wastes from wastewater to protect our existing aquatic ecosystem. Here, to remove methyl orange azo dye from aqueous solutions, a new p(HEMA-co-AETAC)/VMt ... -
Physically and Chemically Crosslinked, Tannic Acid Embedded Linear PEI-Based Hydrogels and Cryogels with Natural Antibacterial and Antioxidant Properties
(MDPI, 2023)Linear polyethyleneimine (L-PEI) was obtained from the acidic hydrolysis of poly(2-ethyl-2-oxazoline) and employed in the synthesis of physically crosslinked L-PEI hydrogel, PC-L-PEIH, chemically crosslinked L-PEI hydrogel, ... -
Adsorption of methylene blue from aqueous solution using poly(2-acrylamido-2-methyl-1-propanesulfonic acid-co-2-hydroxyethyl methacrylate) hydrogel crosslinked by activated carbon
(Taylor and Francis Ltd., 2023)This study aimed to develop an environmentally friendly, inexpensive, and efficient adsorbent for removing methylene blue (MB) dye from wastewater using a three-dimensional porous poly(2-Acrylamido-2-methyl-1-propanesulfonic ... -
Biocompatible Glycol Chitosan Microgels as Effective Drug Carriers
(MDPI, 2023)Glycol chitosan (GC) is a chitosan (CH) derivative with improved water solubility with regards to CH which affords significant solubility advantages. In this study, microgels of GC as p(GC) were synthesized by a microemulsion ... -
Lab-on-a-chip systems for cancer biomarker diagnosis
(Elsevier B.V., 2023)Lab-on-a-chip (LOC) or micro total analysis system is one of the microfluidic technologies defined as the adaptation, miniaturization, integration, and automation of analytical laboratory procedures into a single instrument ... -
Biosensors for saliva biomarkers
(Academic Press Inc., 2023)The analysis of salivary biomarkers has gained interest and is advantageous for simple, safe, and non-invasive testing in diagnosis as well as treatment. This chapter explores the importance of saliva biomarkers and ...
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