Browsing by Author "Ovalı, Mehmet Akif"
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Effects of Ozone Therapy on Chronic Arsenic Poisoning in Rats
Büyük, Başak; Aydeğer, Cemre; Öztopuz, Özlem; Ovalı, Mehmet Akif; Makav, Mustafa; Eroğlu, Hüseyin Avni (Springer, 2023)Arsenic (As) is a toxic metalloid that affects many organs through drinking water. This study aims to examine the efficacy of ozone therapy on chronic arsenic toxicity. Twenty-four male Wistar albino rats were housed in ... -
Melatonin ameliorates cardiac remodelling in fructose‑induced metabolic syndrome rat model by using genes encoding cardiac potassium ion channels
Ovalı, Mehmet Akif; Öztopuz, Özlem; Vardar, Selma Arzu (Springer, 2021)Background Metabolic syndrome comprises a group of disorders, including cardiac abnormalities. Ventricular arrhythmias observed in metabolic syndrome are due to the impaired ventricular repolarization. This study aims to ... -
Neuroprotective Effects of Piceatannol on Olfactory Bulb Injury after Subarachnoid Hemorrhage
Akar, Ali; Öztopuz, Rahime Özlem; Büyük, Başak; Ovalı, Mehmet Akif; Aykora, Damla; Malçok, Ümit Ali (Springer, 2023)Subarachnoid hemorrhage (SAH) accounts for 5% of all stroke cases and is responsible for significant permanent brain and neurological damage within the first few days. Loss of smell is one of those neurological disorders ... -
The role of AQP3 and AQP4 channels in cisplatin‑induced cardiovascular edema and the protective efect of melatonin
Koral, Lokman; Ovalı, Mehmet Akif; Tüfekçioğlu, Nezahat Kübra; Karakılıç, Ersen; Adalı, Yasemen; Uzun, Metehan (Springer, 2021)Background The present study evaluates the development of edema, the change in the AQP3, AQP4, p53 and Bax gene expressions, and the protective efects of melatonin in rat hearts administered with cisplatin. Methods and ... -
Thymol regulates the Endothelin-1 at gene expression and protein synthesis levels in septic rats
Şehitoğlu, Müşerref Hilal; Öztopuz, Rahime Özlem; Kılınç, Namık; Ovalı, Mehmet Akif; Büyük, Başak; Gülçin, İlhami (Elsevier Ireland Ltd, 2023)Sepsis is a serious systemic inflammatory response to infections. In this study, effects of thymol treatments on sepsis response were investigated. A total of 24 rats were randomly divided into 3 different treatment groups, ...