Browsing by Author "Kaplan, Merve"
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Bovine Colostrum and Its Potential for Human Health and Nutrition
Arslan, Ayşenur; Kaplan, Merve; Duman, Hatice; Bayraktar, Ayşe; Karav, Sercan; Ertürk, Melih; Henrick, Bethany M.; Frese, Steven A. (Frontiers Media S.A., 2021)Colostrum is the first milk produced post-partum by mammals and is compositionally distinct from mature milk. Bovine colostrum has a long history of consumption by humans, and there have been a number of studies investigating ... -
Determining Total Protein and Bioactive Protein Concentrations in Bovine Colostrum
Arslan, Ayşenur; Duman, Hatice; Kaplan, Merve; Uzkuç, Hasan; Bayraktar, Ayşe; Erturk, Melih; Alkan, Merve; Karav, Sercan (Journal of Visualized Experiments, 2021)Colostrum is a complex biological fluid produced by mammals immediately after parturition. It meets all the nutritional requirements for neonates as a good source of macro-and micronutrients, bioactive peptides, and growth ... -
A novel in-vitro digestion model designed by integration of microbiome associated enzymes
Kaplan, Merve (Çanakkale Onsekiz Mart Üniversitesi, Lisansüstü Eğitim Enstitüsü, 2022)İnsan mikrobiyotası, milyonlarca sayıda mikroorganizma içermektedir ve bu mikroorganizmalar beyin bağırsak etkileşimi ve enerji metabolizması gibi birçok önemli biyolojik fonksiyonda görev almaktadır. Özellikle, birçok ... -
Phage-encoded carbohydrate-interacting proteins in the human gut
Rothschild-Rodriguez, Daniela; Hedges, Morgen; Kaplan, Merve; Karav, Sercan; Nobrega, Franklin L. (Frontiers Media S.A., 2023)In the human gastrointestinal tract, the gut mucosa and the bacterial component of the microbiota interact and modulate each other to accomplish a variety of critical functions. These include digestion aid, maintenance of ... -
Potential Applications of Endo-beta-N-Acetylglucosaminidases From Bifidobacterium longum Subspecies infantis in Designing Value-Added, Next-Generation Infant Formulas
Duman, Hatice; Kaplan, Merve; Arslan, Ayşenur; Şahutoglu, Arif Sercan; Karav, Sercan; Kayılı, Hacı Mehmet; Frese, Steven A. (Frontiers Media S.A., 2021)Human milk is the optimal source of infant nutrition. Among many other health benefits, human milk can stimulate the development of a Bifidobacterium-rich microbiome through human milk oligosaccharides (HMOs). In recent ... -
Recombinant Production of Bifidobacterial Endoglycosidases for N-glycan Release
Sucu, Berfin; Bayraktar, Ayşe; Duman, Hatice; Arslan, Ayşenur; Kaplan, Merve; Karyelioğlu, Melda; Ntelitze, Eda; Taştekin, Taner; Yetkin, Seray; Karav, Sercan (Journal of Visualized Experiments, 2021)Protein glycosylation is a diverse and common post-translational modification that has been associated with many important roles such as protein function, including protein folding, stability, enzymatic protection, and ... -
Release of bifidogenic N-glycans from native bovine colostrum proteins by an endo-β-N-acetylglucosaminidase
Bunyatratchata, Apichaya; Parc, Annabelle Le; de Moura Bell, Juliana Maria Leite Nobrega; Cohen, Josh L.; Duman, Hatice; Arslan, Ayşenur; Kaplan, Merve; Barile, Daniela; Karav, Sercan (Elsevier Inc., 2023)Milk glycoproteins play various biological roles including antibacterial, antiviral activities, modulating immune responses in living organisms. Released N-glycans from milk glycoproteins act as growth substrates for ...
