Browsing by Author "Dönmez, Serhat"
Now showing items 1-3 of 3
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Elucidating the anticancer activities of novel triarylbenzophenone derivatives by mechanism-based and in silico approaches
Dönmez, Serhat (Çanakkale Onsekiz Mart Üniversitesi, 2023)Son zamanlarda çok hedefli ilaçların geliştirilmesi kanser tedavisinde kullanılan stratejilerden biridir. Bu strateji, ilaçların etki gücünü arttırmakla beraber istenmeyen yan etkileri de azaltmaktadır. Bu çalışmada, özgün ... -
Looking at NSAIDs from a historical perspective and their current status in drug repurposing for cancer treatment and prevention
Özleyen, Adem; Yılmaz, Yakup Berkay; Dönmez, Serhat; Atalay, Hazal Nazlıcan; Antika, Gizem; Boyuneğmez Tümer, Tuğba (Springer Science and Business Media Deutschland GmbH, 2023)Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most frequently prescribed drug classes with wide therapeutic applications over the centuries. Starting from the use of salicylate-containing willow leaves to ... -
Synthesis of Selagibenzophenone A and Its Derivatives for Evaluation of Their Antiproliferative, ROR gamma Inverse Agonistic, and Antimicrobial Effect
Lapinskaite, Ringaile; Atalay, Hazal Nazlıcan; Malatinec, Stefan; Dönmez, Serhat; Çınar, Zeynep Özlem; Schwarz, Patrik F. F.; Perhal, Alexander F. F.; Tümer Boyuneğmez, Tuğba (John Wiley and Sons Inc, 2023)We report a modular synthetic approach towards novel derivatives of the naturally occurring arylated benzophenone selagibenzophenone A. The initial strategy for the construction of the carbon framework of the derivatives ...
