Browsing by Author "Cömert Önder, Ferah"
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Major Bioactive Prenylated Flavonoids from Humulus lupulus L., Their Applications in Human Diseases and Structure-Activity Relationships (SAR) - A Review
Cömert Önder, Ferah; Kalın, Sevil; Şahin, Nebahat; Davutlar, Gülce; Abusharkh, Khaled A.N.; Maraba, Özlem; Ay, Mehmet; Hal, Rabia Selina (Tabriz University of Medical Sciences, 2024)In recent years, the incidence of cancers, inflammatory diseases, Alzheimer's disease, glucose metabolism disorder and diabetes has increased alarmingly which demands more research into the discovery of new drug candidates ... -
Nitro Compounds Inhibit Breast Cancer Cell Proliferation, Migration, and Colony Formation: Molecular Docking, Molecular Dynamics Simulations and Pharmacological Properties
Cömert Önder, Ferah; Şahin, Nebahat; Davutlar, Gülce; Önder, Alper; Ay, Mehmet (John Wiley and Sons Inc, 2023)In this study, the concept of combined in vitro and in silico studies were utilized by using some synthesized nitro bearing compounds. The anticancer activities of the studied compounds were performed by using colony ... -
Target-Driven Design of a Coumarinyl Chalcone Scaffold Based Novel EF2 Kinase Inhibitor Suppresses Breast Cancer Growth In Vivo
Cömert Önder, Ferah; Kahraman, Nermin; Bellur Atıcı, Esen; Çağır, Ali; Kandemir, Hakan; Tatar, Gizem; Ay, Mehmet (Amer Chemical Soc, 2021)Eukaryotic elongation factor 2 kinase (eEF-2K) is an unusual alpha kinase involved in protein synthesis through phosphorylation of elongation factor 2 (EF2). eEF-2K is highly overexpressed in breast cancer, and its activity ...
