Browsing by Author "Büyük, Başak"
Now showing items 1-10 of 10
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Alterations in aquaporin gene expression level on cyclophosphamide-induced cardiac injury and possible protective role of Ganoderma lucidum
Öztopuz, Özlem; Coşkun, Özlem; Büyük, Başak (Springer, 2021)This research study was conducted to investigate the cardioprotective activity of alcoholic extract of Ganoderma lucidum (GL) against cyclophosphamide (CYP)-induced cardiotoxicity in rats model. Therewithal, the regulation ... -
The Effect of Chronic Intermittent Cold Exposure on Gastrin-, Somatostatin-, Secretin-, and Serotonin-Containing Cells in the Small Intestine of Rats
Yıldız, Mustafa; Büyük, Başak; Kanbur, Savaş (Springer, 2021)Stress is counted among the reasons of many diseases. Exposure to cold is one of the stimulants that leads to stress. No study has been found in the literature showing how the enteroendocrine cells in the small intestine ... -
The effect of medical ozone on oxidative stress and neuroinflammation in the early stage after experimental status epilepticus
Çokyaman, Turgay; Öztopuz, Özlem; Coşkun, Özlem; Büyük, Başak; Kiraz, Hasan Ali; Elmas, Sait (Springer, 2021)Preservation of the brain is important to reducing recurrent seizures and other neurological sequelae after status epilepticus (SE). Medical ozone (MedO3) shows antioxidant, anti-inflammatory and anti-apoptotic properties ... -
The Effect of Topically Applied Boric Acid on Ephrin-Eph Pathway in Wound Treatment: An Experimental Study
Büyük, Başak; Aydeğer, Cemre; Adalı, Yasemen; Eroğlu, Hüseyin Avni (SAGE Publications, Early Acce)Background: Wound healing has a vital importance for the organism and various agents are used to accelerate wound healing. Although the effect of boron on wound healing is known, its mechanisms are not completely clear ... -
EFFECTS OF DIFFERENT DOSES OF SHIITAKE MUSHROOM (LENTINUS EDODES) ON SPERM PARAMETERS AND TESTICULAR TISSUE IN RATS: AN EXPERIMENTAL STUDY
Büyük, Başak; Demir, Neslihan; Eroğlu, Hüseyin Avni; Öztopuz, Rahime Özlem (Pakistan Agricultural Scientists Forum, 2023)Lentinus edodes has been cultivated and used as food and medicine in far eastern countries.The present study aimed to reveal whether L.edodes that is used for different purposes has a toxic effect on the male genital system ... -
Effects of Ozone Therapy on Chronic Arsenic Poisoning in Rats
Büyük, Başak; Aydeğer, Cemre; Öztopuz, Özlem; Ovalı, Mehmet Akif; Makav, Mustafa; Eroğlu, Hüseyin Avni (Springer, 2023)Arsenic (As) is a toxic metalloid that affects many organs through drinking water. This study aims to examine the efficacy of ozone therapy on chronic arsenic toxicity. Twenty-four male Wistar albino rats were housed in ... -
The Effects of Thiopental on Cold Ischemic Injury in Renal Transplantation
Büyük, Başak; Adalı, Yasemen; Karakoç, Ebru; Eroğlu, Hüseyin Avni; Aydeğer, Cemre (Medical University of Plovdiv, 2023)Introduction: One of the most important factors influencing post-transplant success in kidney transplantation is preserving the viability of the organ from removal to transfer into the recipient. Aim: This study aimed to ... -
Neuroprotective Effects of Piceatannol on Olfactory Bulb Injury after Subarachnoid Hemorrhage
Akar, Ali; Öztopuz, Rahime Özlem; Büyük, Başak; Ovalı, Mehmet Akif; Aykora, Damla; Malçok, Ümit Ali (Springer, 2023)Subarachnoid hemorrhage (SAH) accounts for 5% of all stroke cases and is responsible for significant permanent brain and neurological damage within the first few days. Loss of smell is one of those neurological disorders ... -
Possible protective activity of n‑acetyl cysteine against cisplatin‑induced hepatotoxicity in rats
Coşkun, Özlem; Öztopuz, Özlem; Büyük, Başak (Springer, 2021)CP is one of the most widely used antineoplastic agents. However, its clinical application is very limited due to its severe toxic efects. The present study aimed to reveal the efects of NAC, which exhibits broad biological ... -
Thymol regulates the Endothelin-1 at gene expression and protein synthesis levels in septic rats
Şehitoğlu, Müşerref Hilal; Öztopuz, Rahime Özlem; Kılınç, Namık; Ovalı, Mehmet Akif; Büyük, Başak; Gülçin, İlhami (Elsevier Ireland Ltd, 2023)Sepsis is a serious systemic inflammatory response to infections. In this study, effects of thymol treatments on sepsis response were investigated. A total of 24 rats were randomly divided into 3 different treatment groups, ...