Browsing by Author "Aydın, Elif Burcu"
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Advances in immunosensor technology
Aydın, Muhammet; Aydın, Elif Burcu; Sezgintürk, Mustafa Kemal (Academic Press Inc., 2021)In recent years, advances in immunosensor device fabrication have significantly expanded the use of this technology in a broad range of applications including clinical diagnosis, food analysis, quality control, environmental ... -
Biosensors for saliva biomarkers
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Academic Press Inc., 2023)The analysis of salivary biomarkers has gained interest and is advantageous for simple, safe, and non-invasive testing in diagnosis as well as treatment. This chapter explores the importance of saliva biomarkers and ... -
Detection of Kallikrein-Related Peptidase 4 with a Label-free Electrochemical Impedance Biosensor Based on a Zinc(II) Phthalocyanine Tetracarboxylic Acid-Functionalized Disposable Indium Tin Oxide Electrode
Aydın, Elif Burcu; Aydın, Muhammet; Yüzer, Abdülcelil; İnce, Mine; Ocakoğlu, Kasım; Sezgintürk, Mustafa Kemal (Amer Chemical Soc, 2021)A new impedimetric biosensing system based on kallikrein-related peptidase 4 (KLK 4) antigen-specific antibodies and a zinc(II) phthalocyanine tetracarboxylic acid (Zn-PcTCa) matrix material was developed for the first ... -
Electrochemical Immunosensor for Detection of CCR4 Cancer Biomarker in Human Serum: An Alternative Strategy for Modification of Disposable ITO Electrode
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Wiley-VCH Verlag, 2021)Herein, a new strategy for the fabrication of a sensitive immunosensor capable of determination of CC Chemokine receptor 4 (CCR4) in complex serum samples is developed through the polymer modification on the disposable ... -
Fabrication of electrochemical immunosensor based on acid-substituted poly(pyrrole) polymer modified disposable ITO electrode for sensitive detection of CCR4 cancer biomarker in human serum
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Elsevier, 2021)This study described the first impedimetric immunosensor reported for the determination of CCR4, a new prostate cancer biomarker. This impedimetric immunosensor was constructed through the modification of disposable indium ... -
Fabrication of Electrochemical Immunosensor for Detection of Interleukin 8 Biomarker via Layer-by-layer Self-assembly Process on Cost-effective Fluorine Tin Oxide Electrode
Aydın, Elif Burcu; Sezginturk, Mustafa Kemal (Wiley, 2021)A highly sensitive impedimetric immunosensor for the determination of interleukin 8 (IL 8) cancer biomarker was fabricated via simple fabrication process. A silane agent with isocyanate groups, 3-(triethoxysilyl)propyl ... -
Highly selective and sensitive sandwich immunosensor platform modified with MUA-capped GNPs for detection of spike Receptor Binding Domain protein: A precious marker of COVID 19 infection
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Elsevier, 2021)A label-free electrochemical biosensing system as a suitable analysis technique for COVID 19 specific spike receptor-binding domain protein (RBD) was developed with an aim to facilitate the diagnosis of coronavirus. A novel ... -
Immunosensors Based on the Technology of Molecular Imprinted Polymers
Aydın, Elif Burcu; Aydın, Muhammed; Sezgintürk, Mustafa Kemal (Elsevier, 2021)Molecularly imprinted polymer (MIP)-based biosensors have successfully been utilized for sensitive and selective biosensing of different analytes because of imprinted molecular cavities present on the transducer surface. ... -
A Label-free Electrochemical Immunosensor for Highly Sensitive Detection of TNF alpha, Based on Star Polymer-modified disposable ITO Electrode
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Bentham Science Publishers, 2021)Background: Biomarkers are very important disease-related biomolecules which should be analyzed sensitive and selective in related physiological fluids or tissues. Tumor necrosis factor-α is a type of cytokine which plays ... -
A new immunosensing platform based on conjugated Poly(ThidEp-co-EDOT) copolymer for resistin detection, a new obesity biomarker
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Springer, 2024)The design of a novel electrochemical impedimetric biosensor for label-free analysis of resistin, a biomarker for obesity, is reported. For the fabrication of the immunosensor, a novel approach composed of electrochemical ... -
New Impedimetric Sandwich Immunosensor for Ultrasensitive and Highly Specific Detection of Spike Receptor Binding Domain Protein of SARS-CoV-2
Aydın, Elif Burcu; Aydın, Muhammet (Amer Chemical Soc, 2021)An impedance sensing platform-combined conducting nanocomposite layer was fabricated to develop an effective and rapid method for detection of coronavirus infection (COVID-19) specific spike receptor binding domain (RBD) ... -
A novel electrochemical immunosensor based on acetylene black/ epoxy-substituted-polypyrrole polymer composite for the highly sensitive and selective detection of interleukin 6
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Elsevier, 2021)An ultrasensitive immunosensor based on acetylene black (AB)/epoxy-substituted-poly(pyrrole) polymer (EpxS-PPyr) composite coated disposable indium tin oxide (ITO) electrode was fabricated for interleukin 6 (IL 6) detection. ... -
A novel electrochemical impedance immunosensor for the quantification of CYFRA 21-1 in human serum
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (Springer, 2023)A sensitive, simple, and reliable immunosensor was constructed to detect the lowest alteration of a fragment of cytokeratin subunit 19 (CYFRA 21-1), a protein lung carcinoma biomarker. The proposed immunosensor was ... -
A Simple and Low-Cost Electrochemical Immunosensor for Ultrasensitive Determination of Calreticulin Biomarker in Human Serum
Aydın, Elif Burcu; Aydın, Muhammet; Sezgintürk, Mustafa Kemal (John Wiley and Sons Inc, 2023)An early on time detection of breast cancer significantly affects the treatment process and outcome. Herein, a new label-free impedimetric biosensor is developed to determine the lowest change in the level of calreticulin ... -
Ultrasensitive and Selective Impedimetric Determination of Prostate Specific Membrane Antigen Based on Di-Succinimide Functionalized Polythiophene Covered Cost-Effective Indium Tin Oxide
Aydın, Elif Burcu; Aydın, Muhammet; Sezginturk, Mustafa Kemal (John Wiley and Sons Inc, 2021)A new and ultrasensitive impedimetric biosensor fabricated by using conjugated di-succinimide substituted polythiophene (P(ThidiSuc)) polymer modified indium tin oxide electrode is developed for the first time to detect ... -
Ultrasensitive detection of interleukin 1α using 3-phosphonopropionic acid modified FTO surface as an effective platform for disposable biosensor fabrication
Aydın, Elif Burcu; Sezgintürk, Mustafa Kemal (Elsevier B.V., 2021)In this study, we utilized a carboxyalkylphosphonic acid covered fluorine doped tin oxide (FTO) as an electrode material for fabrication of Interleukin 1α (IL-1α) immunosensor. For this aim, anti-IL-1α antibodies were ... -
Ultrasensitive detection of NSE employing a novel electrochemical immunosensor based on a conjugated copolymer
Aydın, Muhammet; Aydın, Elif Burcu; Sezgintürk, Mustafa Kemal (Royal Society of Chemistry, 2024)In the current study a simple and highly specific label-free impedimetric neuron specific enolase (NSE) immunosensor based on a copolymer matrix-coated disposable electrode was designed and tested. The copolymer matrix was ...
