Browsing by Author "Özleyen, Adem"
Now showing items 1-4 of 4
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Biofortified Whey/Deglycosylated Whey and Chickpea Protein Matrices: Functional Enrichment by Black Mulberry Polyphenols
Özleyen, Adem; Çınar, Zeynep Özlem; Karav, Sercan; Bayraktar, Ayşe; Arslan, Ayşenur; Kayılı, H. Mehmet; Salih, Bekir; Boyuneğmez Tümer, Tuğba (Springer, 2022)Morus nigra L. (black mulberry-BM) is a promising nutraceutical fruit containing biologically active polyphenols like anthocyanins, proanthocyanidins, catechins, and stilbenes, with well-established anti-inflammatory, ... -
Dataset on the differentiation of THP-1 monocytes to LPS inducible adherent macrophages and their capacity for NO/iNOS signaling
Özleyen, Adem; Yılmaz, Yakup Berkay; Boyuneğmez Tümer, Tuğba (Elsevier Inc., 2021)When THP-1 cells are differentiated into adherent macro-phage-like cells, they respond to inflammatory stimuli by changing their phenotypes to an activation state and altering the expression of inflammation-related genes. ... -
Looking at NSAIDs from a historical perspective and their current status in drug repurposing for cancer treatment and prevention
Özleyen, Adem; Yılmaz, Yakup Berkay; Dönmez, Serhat; Atalay, Hazal Nazlıcan; Antika, Gizem; Boyuneğmez Tümer, Tuğba (Springer Science and Business Media Deutschland GmbH, 2023)Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most frequently prescribed drug classes with wide therapeutic applications over the centuries. Starting from the use of salicylate-containing willow leaves to ... -
New nimesulide derivatives with amide/sulfonamide moieties: Selective COX-2 inhibition and antitumor effects
Güngör, Tuğba; Özleyen, Adem; Yılmaz, Yakup Berkay; Siyah, Pınar; Ay, Mehmet; Boyuneğmez Tümer, Tuğba (Elsevier Masson s.r.l., 2021)Seventeen new amide/sulfonamide containing nimesulide derivatives were synthesized and characterized by several spectroscopic techniques and primarily investigated for their inhibitory potential on COX enzymes and other ...
